posted: November 2, 2023

updated: November 2, 2023

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bonafide relizen and estroven

Menopause symptoms can be very difficult to manage. Thankfully there are some good over-the-counter options out there including Relizen and Estroven.

I'm going to compare and contrast both menopause relief supplements, taking a critical look at each product. We'll begin with The Hot Takes!

The Hot Takes of Estroven vs Relizen

  • Relizen should be taken for three months in order to be effective for relieving a variety of menopause symptoms.
  • Relizen is a non-hormonal menopause supplement that is made from pollen extract. Don’t worry; it has been processed in a manner that removes allergens.
  • It’s difficult to say whether Relizen is safe aside from initial studies. The FDA doesn’t study or regulate pollen-based supplements.
  • Estroven may also require a few months before it starts working.
  • Estroven can reduce menopause-related symptoms without the use of prescription medication or hormone therapy.
  • Some reviews state that Estroven Complete Multi-Symptom Menopause Relief worked for some of their symptoms but not all.

Overview of Relizen

bonafide relizen bottle

Using the natural active ingredient of powdered pollen extract, Relizen has been around for a couple of decades. However, it’s been branded with a few different names over the years (Femal, Serelys and PureCyTonin). Manufactured by the Bonafide Health LLC company, Relizen claims to relieve a number of symptoms associated with menopause. This includes:

  • Hot flashes
  • Night sweats
  • Mood fluctuations
  • Weight gain
  • Poor quality sleep
  • Tiredness

Minimal studies have been performed to really understand how Bonafide pollen can help support your body and mind through this transitional period. However, it has been suggested that Relizen has an impact on serotonin production. The pollen in Bonafide’s Relizen also possesses a strong antioxidant composition that can positively impact things like hot flashes, sleep quality and mood. This is a completely hormone-free supplement that is a much safer alternative to prescription hormone replacement therapy.

What I Like

  • There doesn’t appear to be any potential drug interactions when using Relizen.
  • This is a hormone-free option for supporting your body through the transitional period of menopause.
  • Depending on your insurance, you may be able to use your FSA or HAS account to cover the cost of Relizen.
  • It’s a relatively affordable product, especially when you purchase multiple months’ worth at one time.

What I Don’t Like

  • You may not see the full potential of this product until you’ve taken it for three months.
  • There are some possible side effects, which include headaches, GI upset, irritability and sinus congestion. Bonafide only addresses the fact that there are no known hormonal side effects when using this product.
  • This supplement can impact your serotonin levels, but the Bonafide brand claims that it is very safe to take with other medications. If you’re taking any kind of medication that affects your serotonin levels, it’s best to check with a medical professional before starting Relizen.
  • If you’re interested in improving symptoms associated with vaginal dryness or vaginal discomfort, you may also need to use Bonafide’s Ristela or Revaree.

Cost and Where to Buy

You can purchase Relizen directly through the Bonafide website. The current cost is $57 for a single box. However, you can save some money by signing up for the three-month plan. Since it’s recommended that you take Relizen for at least three months to see its full potential, it makes sense to buy more than one month. The price is $37 per month for the 3-month plan.

relizen tablets in hand

Overview of Estroven

estroven complete multi-symptom box

Also, a drug-free and hormone-free menopause supplement, Estroven Complete Multi-Symptom Menopause Relief uses rhapontic rhubarb as its active ingredient. The company claims you can reduce night sweats and hot flashes by up to 90 percent. You can use it for different stages of menopause, including perimenopause. Estroven doesn’t raise your estrogen levels, eliminating the risks that are associated with hormone-based therapies (such as an increased risk of cancer and blood clots). Estroven is a relatively clean product that is also very affordable.

What I Like

  • It’s incredibly affordable compared to other natural menopause-relief products. It costs $19.99 for a one-time purchase. A discount is available if you sign up for a subscription.
  • Estroven is natural and free of hormones. It won’t impact your natural estrogen production.
  • Estroven claims that you can use their Multi-Symptom Menopause Relief supplement to alleviate all of the major symptoms associated with the different stages of menopause.
  • A two-year-long study was performed on the safety of this product and its effectiveness.

What I Don’t Like

  • It would be nice if Estroven conveniently included links on their website to the different studies that they claim have been done on their products.
  • You may see some relief in as little as 28 days, but it may take a few months to see the full potential of this product.
  • Some reviews state that there weren’t any positive results experienced with the use of this product.

Cost and Where to Buy

You can purchase Estroven Complete Multi-Symptom Menopause Relief on the Estroven website. The price is currently $19.99 for a one-time purchase. You can also subscribe to save 10% on your order, bringing the price down to $17.99. You control how often you receive deliveries. This product is also available at major retailers like Walmart, BJ’s Wholesale Club and iHerb.

estroven tablet in hand

Comparison Section: Relizen vs Estroven

Product Name






Menopause relief for:

Hot flashes and night sweats

Hot flashes, night sweats, weight management, healthy metabolism

Hormone-free ingredients:



Supplement form and servings:

Small pill, 2 pills per day, 30 servings

Capsule, 1 capsule per day, 30 servings

Buy Now:

Comparing Formulas

Both Relizen and Estroven Multi-Symptom Menopause Relief are similar in that they are made using natural ingredients to provide menopause support. However, their ingredients are very different. Relizen is made using exclusive Bonafide Pollen. Whereas Estroven provides support using rhapontic rhubarb root extract.

Each supplement has some additional ingredients added to simply keep the product stable and absorbable, but neither has any other active ingredients.

supplement facts compared

Comparing Customer Reviews

When you’re a woman shopping for effective support to help you through the unpleasant and uncomfortable symptoms of menopause, you’re probably going to be interested in hearing what other women experienced when trying a specific product. Let’s take a look at some of the customer reviews that we looked at for both Relizen and Estroven.

Relizen has a four-out-of-five-star rating on Bonafide’s website. There are currently almost 900 reviews listed. Among the 500+ positive reviews that are included, many women praise how effective and life changing Relizen is. It helped them manage their menopause symptoms, such as night sweats, hot flashes and mood swings. On the flip side, some women didn’t experience any relief at all when using Relizen. Their symptoms remained just as severe, despite staying diligent with dosing for a number of weeks or months. Bonafide replies to these reviews and explains that this supplement will not work for everyone.

Estroven has a four-out-of-five-star review on the brand’s website. There are almost 400 reviews listed. Results seem to be pretty similar to Relizen. Some women found this product to be very beneficial, whereas there are others who didn’t experience any benefits at all. There have been some adverse reactions when using Estroven, such as skin rashes.

Comparing Pricing and Overall Value

Seeing as how these two menopause-relief products are similar in that they’re natural and drug-free, one would assume that they would be similarly priced. Relizen is a bit more expensive, but it has a bit more science backing it. There are four different types of plants from Sweden that are used to formulate this product. You essentially get what you pay for, and Relizen is made using high-quality ingredients. You can save quite a bit of money if you subscribe for regular deliveries of this product, which is ideal anyway because of the need to take Relizen on an ongoing basis for a number of months.

Estroven is priced under $20, but we find it to be a bit lower quality. In addition to its active ingredient, it also contains things like microcrystalline cellulose, titanium dioxide and maltodextrin.

Main Differences Between Estroven and Relizen

The active ingredient of each menopause supplement is completely different. Relizen uses Bonafide pollen from plants in Sweden. Estroven utilizes rhapontic rhubarb root extract, though we don’t know where this is sourced as this information wasn’t readily available on the company’s website.

The price is also different, but we discussed quality and value. In our opinion, you get safer, higher-quality ingredients from Relizen.

Which Is Better: Relizen or Estroven?

There are a number of factors to consider when you’re selecting a supplement that you want to take for a number of months to hopefully alleviate symptoms associated with menopause. The transparency of a brand is extremely important, and we feel that Bonafide does a good job of explaining what Relizen is, what it can be used for and how it’s made. There are also plenty of reviews on the Bonafide website that you can peruse.

While Estroven is a well-known brand, they don’t have a great deal of reviews listed on their website. You could look into the other reviews that are on the alternative websites where the products are sold, but their legitimacy is questionable. We would appreciate a bit more transparency and easy-to-access information on the Estroven website regarding where ingredients are sourced and direct links to the studies that are mentioned.

We would choose Relizen over Bonafide for these reasons. While you pay a little more for Relizen, the quality seems far superior. The results also seem promising.

About the Author

Lynn Rose is a super talented mom and Certified Nutritionist with a big passion for sharing knowledge. She spent about 10 years working in journalism, where she learned a lot about writing and telling stories. Lynn also worked in radio for about 3 years, doing all sorts of cool jobs like being on the air, directing programs, helping with promotions, and even designing websites. She has a B.A. in Communications. When she's not writing, Lynn loves to try different products and provide in-depth hands-on reviews.

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